Company: PolyPid Ltd.
Symbol: POLY
Description: They are a clinical-stage pharmaceutical company focused on developing and commercializing novel, locally administered therapies using their transformational PLEX (Polymer-Lipid Encapsulation matriX) technology.
Shares: 3.33 million
Price Range: $21.00-$24.00
Trade Date: 3/23
Underwriter(s): Goldman Sachs, Cowen
Co-Manager(s): Cantor, Raymond James, Oppenheimer & Co.
Terms Added: 3-14-18
Business: They are a clinical-stage pharmaceutical company focused on developing and commercializing novel, locally administered therapies using their transformational PLEX (Polymer-Lipid Encapsulation matriX) technology.
They are initially focused on the development of their lead product candidate, D-PLEX100, for the prevention of surgical site infections, or SSIs, in bone and soft tissue. They recently reported interim results from their fully-enrolled Phase 1b/2 clinical trial of D-PLEX100 for the prevention of sternal SSIs after cardiac surgery. During the three-month period after treatment, they observed no sternal wound infections in any of the patients treated with D-PLEX100 in combination with the standard of care. In contrast, they observed a 4.5% infection rate in the control group of patients who received the standard of care alone.
Insider Buying: Certain of our existing shareholders have indicated an interest in purchasing up to an aggregate of $19.5 million in ordinary shares in this offering at the initial public offering price per share.
Collaboration: They are developing D-PLEX500, formerly known as BonyPid-500, with our collaborator, MIS Implants Technologies Ltd., a subsidiary of Dentsply Sirona Inc., for use in periodontal and oral/maxillofacial surgeries to treat peri-implantitis, a destructive inflammatory process affecting the soft and bone tissues surrounding dental implants.
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